Study reports, Biodegradable Chrysotile Fibres break into short fibres and particles which clear by alveolar macrophages.
May 08, 2020
In a scientific study conducted by the seven-member team of international researchers led by D.M. Bernstein. The team published its two-part research in Elsevier’s online Toxicology and Applied Pharmacology journal in December 2019.
A research study evaluating exposure dose-response and fate in the lung and pleura of chrysotile containing brake dust confirms the major differences between the toxicology of chrysotile fibres and that of other asbestos fibres.
This rigorous, 90-day repeated dose inhalation study of brake dust in rats provides a comprehensive understanding of the biokinetics and potential toxicology in the lung. It included a particle control on chrysotile, commercial crocidolite and amosite asbestos.
As per the report, Chrysotile, being biodegradable, showed a weakening of its matrix and braking into short fibers and particles that can be cleared by alveolar macrophages and continued dissolution.